Home is the name of the homeworld of the Al Bhed. You cannot return to Home after you have visited this area which means that if you forgot any items there during your visit (specifically the 
Al Bhed Primers) you will not be able to retrieve them without restarting your game.
As mentioned above, you can only visit Home the one time, and there is no way to revisit the area. SPOILER: The area is destroyed when your party departs from the area. Refer to the walkthrough and strategy guide for more details and to make sure that you don’t miss any of the key items in the area:
